Portrait of Ruffus Possibly 1574

Johannes Sambucus’s *Portrait of Ruffus* is a 16th-century engraving that depicts a bust portrait of the ancient Roman physician Ruffus of Ephesus. The image is presented in a round frame with ornate details including two small, crouching dogs at the top and a serpent entwined with ribbons and a key at the bottom. The engraving is part of a larger series of portraits of ancient physicians by Sambucus. *Portrait of Ruffus* is a fine example of the detailed and precise style of engraving that was popular in the 16th century.